IVF in Natural Cycle is an infertility treatment that follows the same process as conventional IVF, but without the use of hormonal stimulation to produce multiple eggs. Unlike conventional IVF, only one egg is retrieved, which means there will be only one embryo if the egg fertilizes normally. Additionally, around 30% of cycles are canceled due to premature ovulation. Current medical literature shows acceptable clinical pregnancy rates using Natural Cycle IVF, varying between 15-25% per embryo transfer.
What are the Advantages?
✓ No ovarian stimulation medications
✓ Less costly
✓ Can be repeated monthly
✓ Very low risk of multiple pregnancies
✓ No risk of ovarian hyperstimulation syndrome (OHSS)
✓ Fewer side effects, less discomfort, and emotional stress
Stages
Stage I. Ovulation Induction
- Ultrasound monitoring of ovulation and endometrial morphology
- Consultation with the gynecologist
- Ovulation induction with Ovitrelle 0.25 mcg
Stage II. Ovarian Puncture
- Ultrasound-guided ovarian follicle puncture
- Egg retrieval
- Post-procedure recovery
- Consultation and ultrasound after ovarian puncture
Stage III. Embryology Laboratory
- Egg processing
- Sperm processing
- Standard egg fertilization
- Intracytoplasmic sperm injection (ICSI)
- Embryo cultivation in an individual incubator chamber
- Blastocyst culture (optional)
- Laser-assisted hatching
Stage IV. Embryo Transfer
- Ultrasound-guided, microvolume, optimized embryo transfer
- Post-procedure recovery
- Post-transfer consultation
Price
Stage I. Ovulation Induction: €54+
Stage II. Ovarian Puncture: €271
Stage III. Embryology Laboratory: €760
Stage IV. Embryo Transfer: €489
Total: ~ €1,600
Pre-IVF tests are not included in the price. Payments are made in installments before each stage.
Discounts
If the first IVF attempt fails, discounts are offered for subsequent IVF cycles:
- 10% off the 2nd IVF package
- 15% off the 3rd IVF package
- 20% off the 4th IVF package and beyond
Who is IVF in Natural Cycle Recommended For?
- Women with low ovarian reserve or over 40 years old
- Women with poor response to ovarian stimulation in conventional IVF
- Women who do not wish to use hormonal medications
- Male factor infertility
- Tubal factor infertility
- Women with a history of hormone-sensitive cancers or family history of cancer
What are the Disadvantages?
- Lower success rate per cycle compared to conventional IVF
- In 50-70% of cycles, only one embryo may be available for transfer
- Usually, no surplus embryos are available for cryopreservation
- Around 30% of cycles are canceled due to premature ovulation